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Community-acquired pneumonia
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23 V Pneumococcal polysaccharide vaccination (+ 3 months)
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13 V Pneumococcal conjugate vaccination (+10 years)
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Timeline
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Jan–Feb 2005
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May–June 2005
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July–August 2014
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Pneumococcal serotype
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Hospital admission (day 1)
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Recovery (day 42)
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Pre-vaccination
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Post-vaccination
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Pre-vaccination
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Post-vaccination
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3
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0.12
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0.14
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0.05
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2.43
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6.27
|
13.09
|
|
4
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0.06
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0.03
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0.15
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0.17
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0.02
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0.42
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6B
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0.34
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0.33
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0.05
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0.28
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2.63
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42.76
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|
9V
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0.43
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0.25
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0.08
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0.06
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4.06
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15.35
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14
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2.25
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2.67
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3.21
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7.28
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6.91
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9.55
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18C
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3.41
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4.23
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3.76
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49.84
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39.80
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37.41
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19F
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1.03
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1.08
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0.60
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6.85
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31.96
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77.10
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23F
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0.47
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0.55
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0.47
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2.13
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1.55
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17.29
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- A sufficient serotype-specific response is defined as having titers higher than 1.3 μg/ml and at least a two-fold increase between pre- and post-vaccination titers [4]
- Antibody levels to the infecting pneumococcal serotype (9V) are indicated in bold
